a medication myth ・ CYP3A4
A glass of juice can turn one pill into three.
Your gut lining is packed with an enzyme (CYP3A4) whose job is to destroy most of a drug before it ever reaches your blood. Grapefruit shuts that enzyme down — so the same pill sails through and hits like a much bigger dose. It's real, it's dramatic, and it's oddly specific. Pick a medication and pour.
normalwith grapefruit
🍊 grapefruit juice this morning
Piru models this as a real CYP3A4 interaction, per-drug — it knows which of your meds grapefruit touches and which it doesn't. See your own interactions →
← all myths