# The Trial Records

Sole-author preprints in computational pharmacology and language-model interpretability, with their code and data.

## [Measured, borrowed, and unresolved: the target profile of memantine](https://doi.org/10.5281/zenodo.23287829)

Zenodo preprint · 2026-10-10

Published measurements can reverse memantine's predicted preference between NMDA and α7 nicotinic receptors. Same drug, same concentration, opposite target rankings; which receptor explains the clinical benefit remains unresolved. [code & data](https://zenodo.org/records/23287829/files/memantine-reproducibility-2026-10-10.zip?download=1)

## [Predicted metabolites of the methylmethcathinone positional isomers (2-, 3- and 4-MMC) as candidate analytical targets, with in silico hERG-block screening](https://doi.org/10.26434/chemrxiv.15006356/v1)

ChemRxiv preprint · 2026-07-20

What a tox screen should look for once the parent drug is already gone; the cardiac liability mapped alongside.

## [Reading Personality Off the Steering Geometry of a Language Model](https://doi.org/10.5281/zenodo.21440937)

Zenodo preprint · 2026-07-19

A personality instrument derived not by asking the model, but from where its activations bend; the shape was already in the weights. [code](https://github.com/kageroumado/steering-personality)